Disease | werner syndrome |
Symptom | C0231341|premature aging |
Sentences | 3 |
PubMedID- 21076181 | Increased t-sce levels are observed in human cell lines in which the wrn protein has been depleted by sirna, and in cells isolated from a premature aging mouse model of werner syndrome (ws), in which both the gene encoding the wrn helicase and telomerase are deleted . |
PubMedID- 22713343 | Mutations in the wrn gene cause werner syndrome, associated with premature aging, genome instability and cancer predisposition. |
PubMedID- 25372317 | Conclusion: vitreoretinal changes found in this case might have been partially because of the premature aging associated with werner syndrome. |
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